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[通过对有临床症状的肺结核疑似患者进行痰液检查改善病例发现情况]

[Improved case finding by using sputum examination in pulmonary tuberculosis suspects with clinical symptoms].

作者信息

Duanmu Hong-jin, Zheng Su-hua, Xu Biao, Fu Chao-wei

机构信息

Beijing Tuberculosis & Thoracic Tumor Research Institute, Beijing 101149, China.

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 2005 Jul;28(7):468-71.

Abstract

OBJECTIVE

To investigate more effective methods in case finding of tuberculosis (TB).

METHODS

Sputum examination for TB suspects was applied on the basis of traditional chest X-ray screening. TB suspects with cough more than 3 weeks were subjected to a sputum examination firstly. The case finding rate of X-ray screening alone and in combination with sputum examination for TB suspects were compared.

RESULTS

Nine hundred new cases of active pulmonary TB were detected by application of sputum examination to TB suspects, among which 73 more cases were found than X-ray screening alone, and the case detection rate increased 8.8% (73/827). Among the 900 new cases, 30 more cases were found than that of X-ray screening alone in 262 smear positive cases, and the case detection rate increased 12.9%. Three hundred sixty cases were culture positive, among which 63 more cases were found than X-ray screening alone, the case detection rate increased 21.2% (63/297). Among the cases detected by X-ray screening alone, the smear positive rate was 28.1% (232/827), and the culture positive rate was 35.9% (297/827). However, among the cases detected by sputum examination, 29.1% (262/900) was smear positive, and 40.0% (360/900) was culture positive. Among the 73 more cases of active pulmonary TB found by using sputum examination in TB suspects, both the smear positive and the culture positive rates were higher, 41.1% (30/70) and 86.3% (63/73) respectively, as compared to those of cases found by X-ray screening (28.1% and 35.9% respectively).

CONCLUSION

Sputum examination in individuals with symptoms suggestive of pulmonary TB could find out more cases with active disease (21.2%) than chest X-ray screening alone.

摘要

目的

探索更有效的肺结核(TB)病例发现方法。

方法

在传统胸部X线筛查的基础上,对结核病疑似患者进行痰检。首先对咳嗽超过3周的结核病疑似患者进行痰检。比较单独进行X线筛查以及X线筛查联合痰检对结核病疑似患者的病例发现率。

结果

通过对结核病疑似患者进行痰检,共检测出900例活动性肺结核新病例,比单独进行X线筛查多发现73例,病例检出率提高了8.8%(73/827)。在这900例新病例中,262例涂片阳性病例比单独进行X线筛查多发现30例,病例检出率提高了12.9%。360例培养阳性,比单独进行X线筛查多发现63例,病例检出率提高了21.2%(63/297)。单独通过X线筛查检出的病例中,涂片阳性率为28.1%(232/827),培养阳性率为35.9%(297/827)。然而,通过痰检检出的病例中,涂片阳性率为29.1%(262/900),培养阳性率为40.0%(360/900)。在通过对结核病疑似患者进行痰检多发现的73例活动性肺结核病例中,涂片阳性率和培养阳性率均较高,分别为41.1%(30/70)和86.3%(63/73),高于单独通过X线筛查发现的病例(分别为28.1%和35.9%)。

结论

对有肺结核症状的个体进行痰检比单独进行胸部X线筛查能发现更多活动性疾病病例(21.2%)。

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