使用周效磺胺-乙胺嘧啶治疗后恶性疟原虫配子体对阿拉伯按蚊的感染性。
Infectivity of Plasmodium falciparum gametocytes to Anopheles arabiensis after treatment with sulfadoxine-pyrimethamine.
作者信息
Govere J M, Durrheim D N, Mngomezulu N M, Barnes K, Sharp B
机构信息
Communicable Disease Control, Mpumalanga Department of Health, Nelspruit 1200, South Africa.
出版信息
Trans R Soc Trop Med Hyg. 2003 Nov-Dec;97(6):707-8. doi: 10.1016/s0035-9203(03)80108-6.
Abstract
Sulfadoxine-pyrimethamine induces increased gametocytaemia when used for treating Plasmodium falciparum malaria. Laboratory-reared Anopheles arabiensis mosquitoes were fed with blood from patients with post-therapeutic gametocytaemia using a membrane feeder. Fourteen days later the heads and thoraxes of 613 mosquitoes were negative for P. falciparum sporozoites by enzyme-linked immunosorbent assay.
摘要
磺胺多辛-乙胺嘧啶用于治疗恶性疟原虫疟疾时会导致配子体血症增加。使用膜饲器给实验室饲养的阿拉伯按蚊喂食患有治疗后配子体血症患者的血液。14天后，通过酶联免疫吸附测定法，613只蚊子的头部和胸部未检测到恶性疟原虫子孢子。
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