Hagenah Gerrit C, Gueven Elif, Andreas Stefan
Department of Cardiology, University of Marburg, Marburg, Germany.
Respir Med. 2006 Jan;100(1):180-2. doi: 10.1016/j.rmed.2005.04.009. Epub 2005 Aug 22.
In patients with coronary artery disease (CAD) the prevalence of obstructive sleep apnoea (OSA) is found to be about 14-65%. In this study, the influence of OSA in 50 patients with CAD was prospectively compared during a follow-up period of 10 years. In the follow-up period 4 of 25 patients with OSA and 5 of the 25 without OSA died by cardiovascular complications. The proportion survival curve showed no significant difference for patients with CAD and with versus without OSA. The results of this rather small 10-year follow-up study failed to give further evidence for an increased mortality in patients with CAD and OSA.
在冠状动脉疾病（CAD）患者中，阻塞性睡眠呼吸暂停（OSA）的患病率约为14% - 65%。在本研究中，对50例CAD患者进行了前瞻性研究，比较了OSA在10年随访期内的影响。在随访期内，25例OSA患者中有4例、25例无OSA患者中有5例死于心血管并发症。生存比例曲线显示，CAD伴OSA患者与不伴OSA患者之间无显著差异。这项为期10年的小型随访研究结果未能进一步证明CAD合并OSA患者死亡率增加。
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