秘鲁沿海低收入城市人群中2型单纯疱疹病毒感染的流行病学

The epidemiology of herpes simplex virus type 2 infection in low-income urban populations in coastal Peru.

作者信息

Konda Kelika A, Klausner Jeffrey D, Lescano Andres G, Leon Segundo, Jones Franca R, Pajuelo Jose, Caceres Carlos F, Coates Thomas J

机构信息

Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

出版信息

Sex Transm Dis. 2005 Sep;32(9):534-41. doi: 10.1097/01.olq.0000175413.89733.ae.

DOI:10.1097/01.olq.0000175413.89733.ae

PMID:16118601

Abstract

OBJECTIVE

The objective of this study was to determine the epidemiology of herpes simplex virus type 2 (HSV-2) in general and socially marginalized populations of low-income, urban, coastal Peru.

STUDY

Two low-income populations were administered an epidemiologic survey and serologic tests, determining risk behavior, HSV-2, and HIV prevalence.

RESULTS

In the socially marginalized population, HSV-2 prevalence was 72.3% in men who have sex only with men (MSOM), 42.5% in women, and 20.7% in men. In the general population, HSV-2 prevalence was 20.5% in women and 7.1% in men. In all groups except the male general population, HSV-2 prevalence increased with age or number of sexually active years (both P <0.001). HSV-2 infection was associated with HIV infection in MSOM (P <0.023) and other socially marginalized men (P <0.01).

CONCLUSION

HSV-2 was common in both low-income populations, and control programs are needed in Peru given high prevalence and association with HIV infection. Prevention of HSV-2 infection should target individuals before they become sexually active.

摘要

目的

本研究的目的是确定秘鲁沿海城市低收入人群总体及社会边缘化人群中2型单纯疱疹病毒（HSV-2）的流行病学情况。

研究

对两个人数众多的低收入人群进行了流行病学调查和血清学检测，以确定其风险行为、HSV-2及HIV感染率。

结果

在社会边缘化人群中，仅与男性发生性行为者（MSOM）的HSV-2感染率为72.3%，女性为42.5%，男性为20.7%。在普通人群中，女性的HSV-2感染率为20.5%，男性为7.1%。在除男性普通人群外的所有组中，HSV-2感染率均随年龄或性活跃年限的增加而升高（P均<0.001）。在MSOM（P<0.023）及其他社会边缘化男性中（P<0.01），HSV-2感染与HIV感染相关。