Laxmisha C, Thappa D M, Kumar M Senthil, Joseph L C, Jayanthi S
Department of Dermatology & STD Jawaharlal Institute of Post-graduate Medical Education & Research, Pondicherry 605 006, India.
Indian J Lepr. 2004 Oct-Dec;76(4):343-50.
A 22-year-old male student presented to us with patchy sensory loss over the dorsum of right foot of 6 months' duration and swelling over the left index finger of 2 months' duration. Subsequently, a week later, he developed a painful swelling over the left forehead and right leg. On examination, tender soft, fluctuant subcutaneous saccular swellings were seen varying in size from 2x2 cm to 5x5 cm over the left supratrochlear, left radial cutaneous nerve, left digital nerve, right superficial peroneal nerve and left saphenous nerve. The nerves were tender and thickened above and below these cold swellings (cold nerve abscesses). Nerve biopsy of the left radial cutaneous nerve showed granulomatous infiltrate of epithelioid cells, lymphocytes and caseation necrosis of nerve. No bacilli were demonstrated with acid-fast stain. On the basis of the above findings, a diagnosis of pure neuritic leprosy (BT spectrum) in type 1 lepra reaction with multiple nerve abscesses was made. We present this case of pure neuritic leprosy exhibiting multiple nerve abscesses, for its rarity.
一名22岁男性学生前来就诊,其右脚背出现片状感觉丧失已6个月,左手食指肿胀已2个月。随后,一周后,他左侧前额和右腿出现疼痛性肿胀。检查发现,在左侧滑车上、左侧桡神经皮支、左侧指神经、右侧腓浅神经和左侧隐神经处可见大小从2×2厘米至5×5厘米不等的压痛性柔软、波动的皮下囊状肿胀。这些神经在这些冷性肿胀(冷性神经脓肿)的上方和下方压痛且增粗。左侧桡神经皮支的神经活检显示上皮样细胞、淋巴细胞肉芽肿性浸润及神经干酪样坏死。抗酸染色未发现杆菌。基于上述发现,诊断为1型麻风反应中的纯神经炎型麻风(BT型)伴多发神经脓肿。我们报告这例表现为多发神经脓肿的纯神经炎型麻风病例,因其罕见。