Siddaraju Neelaiah, Sistla Sarath Chandra, Singh Neha, Muniraj Femela, Chahwala Qutubuddin, Basu Debdatta, Kumar Surendra
Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.
Diagn Cytopathol. 2009 May;37(5):355-8. doi: 10.1002/dc.21035.
Pure neuritic leprosy (PNL) with nerve abscess manifesting as a huge, cystic, soft tissue mass is highly uncommon. Fine needle aspiration cytology can serve as an important initial diagnostic modality in such an instance. We report a case of 28-year-old male, who presented with a huge swelling in the lower, medial aspect of the right upper arm. The clinical diagnosis was schwannoma. Fine needle aspiration (FNA) yielded 80 ml of sticky, turbid, pale brown fluid. Cytologic examination revealed abundant, caseous, necrotic material and many degenerated neutrophils in a thin proteinaceous background. Stain for acid fast bacilli (AFB) was negative. Based on an AFB negative, caseous, necrotic material obtained from the soft tissue mass located in the ulnar nerve region, a cytodiagnosis of tuberculoid PNL with nerve abscess was given, and this was confirmed by the subsequent histopathologic examination. Our case emphasizes the major role of minimally traumatic, FNA technique in the diagnosis of rare cases of clinically unsuspected neuritic leprosies.
表现为巨大囊性软组织肿块的伴有神经脓肿的纯神经炎型麻风(PNL)极为罕见。在这种情况下,细针穿刺细胞学检查可作为重要的初步诊断方法。我们报告一例28岁男性,其右上臂内侧下部出现巨大肿胀。临床诊断为神经鞘瘤。细针穿刺(FNA)抽出80毫升粘性、浑浊、淡棕色液体。细胞学检查显示在稀薄的蛋白质背景中有大量干酪样坏死物质和许多退化的中性粒细胞。抗酸杆菌(AFB)染色为阴性。基于从位于尺神经区域的软组织肿块中获取的AFB阴性、干酪样坏死物质,做出了伴有神经脓肿的结核样PNL的细胞诊断,随后的组织病理学检查证实了这一诊断。我们的病例强调了微创FNA技术在诊断临床上未被怀疑的罕见神经炎型麻风病例中的主要作用。