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Myocardial dystrophin immunolocalization at sarcolemma and transverse tubules.

作者信息

Yarom R, Morris G E, Froede R, Schaper J

机构信息

Hadassah Medical School, Jerusalem, Israel.

出版信息

Experientia. 1992 Jun 15;48(6):614-6. doi: 10.1007/BF01920250.

DOI:10.1007/BF01920250
PMID:1612140
Abstract

Using monoclonal antibodies against two different regions of the helical rod part of dystrophin, we have localized dystrophin on both plasma membrane and transverse tubules in cardiac muscle of man and several animal species. The staining persisted after experimental ischaemia, and was observed in long-standing heart disease. No immunostaining was seen at the intercalated discs. In skeletal muscle the same two antibodies stained only the plasma membrane.

摘要

相似文献

1
Myocardial dystrophin immunolocalization at sarcolemma and transverse tubules.
Experientia. 1992 Jun 15;48(6):614-6. doi: 10.1007/BF01920250.
2
Dystrophin-glycoprotein complex and laminin colocalize to the sarcolemma and transverse tubules of cardiac muscle.肌营养不良蛋白聚糖复合物和层粘连蛋白共定位于心肌的肌膜和横小管。
Circ Res. 1993 Feb;72(2):349-60. doi: 10.1161/01.res.72.2.349.
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Distinct patterns of dystrophin organization in myocyte sarcolemma and transverse tubules of normal and diseased human myocardium.正常和患病人类心肌细胞肌膜及横管中肌营养不良蛋白组织的不同模式。
Circulation. 2000 Jun 6;101(22):2586-94. doi: 10.1161/01.cir.101.22.2586.
4
Dystrophin predominantly localizes to the transverse tubule/Z-line regions of single ventricular myocytes and exhibits distinct associations with the membrane.肌营养不良蛋白主要定位于单个心室肌细胞的横管/Z线区域,并与细胞膜呈现出明显的关联。
Mol Cell Biochem. 1994 Jan 12;130(1):57-65. doi: 10.1007/BF01084268.
5
Subcellular distribution of dystrophin in isolated adult and neonatal cardiac myocytes.肌营养不良蛋白在分离的成年和新生心肌细胞中的亚细胞分布。
Am J Physiol. 1994 Dec;267(6 Pt 1):C1707-16. doi: 10.1152/ajpcell.1994.267.6.C1707.
6
Dystrophin-glycoprotein complex is highly enriched in isolated skeletal muscle sarcolemma.肌营养不良蛋白-糖蛋白复合物在分离出的骨骼肌肌膜中高度富集。
J Cell Biol. 1991 Jan;112(1):135-48. doi: 10.1083/jcb.112.1.135.
7
Absence of utrophin in intercalated discs of human cardiac muscle.人心脏肌肉闰盘中缺乏抗肌萎缩蛋白。
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Confocal laser microscopy of dystrophin localization in guinea pig skeletal muscle fibers.共聚焦激光显微镜观察豚鼠骨骼肌纤维中肌营养不良蛋白的定位
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Utrophin localization in normal and dystrophin-deficient heart.正常及缺乏抗肌萎缩蛋白的心脏中肌养蛋白的定位
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Dystrophin colocalizes with beta-spectrin in distinct subsarcolemmal domains in mammalian skeletal muscle.在哺乳动物骨骼肌中,肌营养不良蛋白与β-肌动蛋白在不同的肌膜下区域共定位。
J Cell Biol. 1992 Jun;117(5):997-1005. doi: 10.1083/jcb.117.5.997.

引用本文的文献

1
Absence of utrophin in intercalated discs of human cardiac muscle.人心脏肌肉闰盘中缺乏抗肌萎缩蛋白。
Histochem J. 2001 Jan;33(1):9-12. doi: 10.1023/a:1017531627935.
2
Utrophin and dystrophin-associated glycoproteins in normal and dystrophin deficient cardiac muscle.正常及缺乏肌营养不良蛋白的心肌中的肌养蛋白和与肌营养不良蛋白相关的糖蛋白
J Muscle Res Cell Motil. 1999 Apr;20(3):305-14. doi: 10.1023/a:1005426920070.
3
Dystrophin is phosphorylated by endogenous protein kinases.肌营养不良蛋白被内源性蛋白激酶磷酸化。

本文引用的文献

1
Cytoskeletal lesions in anoxic myocardial injury. A conventional and high-voltage electron-microscopic and immunofluorescence study.缺氧性心肌损伤中的细胞骨架病变。一项传统及高压电子显微镜和免疫荧光研究。
Am J Pathol. 1987 Nov;129(2):327-44.
2
Immunoelectron microscopic localization of dystrophin in myofibres.肌营养不良蛋白在肌纤维中的免疫电子显微镜定位
Nature. 1988 Jun 30;333(6176):863-6. doi: 10.1038/333863a0.
3
Immunostaining of skeletal and cardiac muscle surface membrane with antibody against Duchenne muscular dystrophy peptide.用抗杜氏肌营养不良肽抗体对骨骼肌和心肌表面膜进行免疫染色。
Biochem J. 1993 Jul 1;293 ( Pt 1)(Pt 1):243-7. doi: 10.1042/bj2930243.
4
Localization of dystrophin and beta-spectrin in vacuolar myopathies.肌营养不良蛋白和β-血影蛋白在空泡性肌病中的定位
Am J Pathol. 1993 Oct;143(4):1200-8.
Nature. 1988 Jun 30;333(6176):861-3. doi: 10.1038/333861a0.
4
Transcription of the dystrophin gene in human muscle and non-muscle tissue.肌营养不良蛋白基因在人体肌肉和非肌肉组织中的转录。
Nature. 1988 Jun 30;333(6176):858-60. doi: 10.1038/333858a0.
5
Dystrophin diagnosis: comparison of dystrophin abnormalities by immunofluorescence and immunoblot analyses.
Proc Natl Acad Sci U S A. 1989 Sep;86(18):7154-8. doi: 10.1073/pnas.86.18.7154.
6
Association of dystrophin and an integral membrane glycoprotein.肌营养不良蛋白与一种整合膜糖蛋白的关联。
Nature. 1989 Mar 16;338(6212):259-62. doi: 10.1038/338259a0.
7
Increased activity of calcium leak channels in myotubes of Duchenne human and mdx mouse origin.杜兴氏人类肌管和mdx小鼠肌管中钙泄漏通道活性增加。
Science. 1990 Nov 2;250(4981):673-6. doi: 10.1126/science.2173137.
8
Regions of the skeletal muscle dihydropyridine receptor critical for excitation-contraction coupling.骨骼肌二氢吡啶受体中对兴奋-收缩偶联至关重要的区域。
Nature. 1990 Aug 9;346(6284):567-9. doi: 10.1038/346567a0.
9
Localization of dystrophin relative to acetylcholine receptor domains in electric tissue and adult and cultured skeletal muscle.肌营养不良蛋白在电组织以及成年和培养的骨骼肌中相对于乙酰胆碱受体结构域的定位。
J Cell Biol. 1991 Jun;113(5):1133-44. doi: 10.1083/jcb.113.5.1133.
10
Late potentials in progressive muscular dystrophy of the Duchenne type.杜氏型进行性肌营养不良中的晚电位
Am Heart J. 1991 Apr;121(4 Pt 1):1137-42. doi: 10.1016/0002-8703(91)90674-7.