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通过调节自身肝脏的静脉流出道来克服辅助性部分原位肝移植中的门静脉窃血现象。

Overcoming the portal steal phenomenon in auxiliary partial orthotopic liver transplantation by modulation of the venous outflow of the native liver.

作者信息

Broering Dieter C, Walter Jessica, Bassas Atef F

机构信息

Department of Hepatobiliary Surgery and Transplantation, University Hospital of Hamburg-Eppendorf, Germany.

出版信息

Liver Transpl. 2005 Sep;11(9):1140-3. doi: 10.1002/lt.20535.

Abstract

The main drawback of auxiliary partial orthotopic liver transplantation (APOLT) is the competition of the portal flow between the graft and the native liver, leading to graft failure. In two patients with Crigler-Najjar syndrome type I, the intrahepatic resistance of the native liver was increased by occluding the recipients middle hepatic vein during parenchymal transection, leading the portal flow towards the graft. This new surgical technique could encourage centers to recommence APOLT.

摘要

辅助性部分原位肝移植(APOLT)的主要缺点是移植肝与自体肝之间门静脉血流的竞争,从而导致移植肝衰竭。在两名I型克里格勒-纳贾尔综合征患者中,在实质横断时通过阻断受体的肝中静脉增加了自体肝的肝内阻力,使门静脉血流流向移植肝。这种新的手术技术可能会促使各中心重新开展APOLT。

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