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脑室内鳞状乳头型颅咽管瘤:一例术中印片细胞学报告

Intraventricular squamous papillary craniopharyngioma: report of a case with intraoperative imprint cytology.

作者信息

Madhavan Manoharan, P Jain George, Abdullah Jafri J, Idris Zamzuri

机构信息

Department of Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.

出版信息

Acta Cytol. 2005 Jul-Aug;49(4):431-4. doi: 10.1159/000326179.

Abstract

BACKGROUND

Squamous papillary craniopharyngioma is a distinct entity, and its cytologic features may be misleading. Because of the rarity of this tumor, this case is being reported with a note on the cytologic features.

CASE

A 56-year-old Malay man who had 1-month history of generalized lethargy was admitted for altered sensorium. On examination, he was found to have neck stiffness, bilateral papilledema and generalized atrophy of muscles, with reduced power in all limbs. Magnetic resonance imaging of the brain showed a solid mass in the third ventricle causing obstructive hydrocephalus. Intraoperative cytology of the mass diagnosed intraventricular meningioma. However, the final histopathologic examination revealed squamous papillary craniopharyngioma.

CONCLUSION

Craniopharyngioma, squamous papillary type, is a rare entity and usually occurs in adults as an intraventricular solid tumor. Awareness of this entity will aid in arriving at the correct cytologic diagnosis.

摘要

背景

鳞状乳头型颅咽管瘤是一种独特的实体瘤,其细胞学特征可能具有误导性。由于该肿瘤罕见,现报告此病例并对其细胞学特征加以说明。

病例

一名56岁的马来男性,有1个月全身乏力病史,因意识改变入院。检查发现,他有颈部强直、双侧视乳头水肿及全身肌肉萎缩,四肢肌力减弱。脑部磁共振成像显示第三脑室内有一实性肿块,导致梗阻性脑积水。肿块的术中细胞学检查诊断为脑室内脑膜瘤。然而,最终的组织病理学检查显示为鳞状乳头型颅咽管瘤。

结论

鳞状乳头型颅咽管瘤是一种罕见的实体瘤,通常发生于成人,为脑室内实性肿瘤。认识这一实体瘤将有助于做出正确的细胞学诊断。

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