阿维链霉菌中脂肪酸和阿维菌素生物合成的氮调节
Nitrogen regulation of fatty acids and avermectins biosynthesis in Streptomyces avermitilis.
作者信息
Novák J, Hájek P, Rezanka T, Vanĕk Z
机构信息
Institute of Microbiology, Prague, Czechoslovakia.
出版信息
FEMS Microbiol Lett. 1992 May 15;72(1):57-61. doi: 10.1016/0378-1097(92)90489-b.
PMID:1612418
Abstract
Fatty acid composition was analysed in the producer of avermectins, Streptomyces avermitilis C-18 grown in chemically defined medium with different nitrogen sources. Significant differences in nitrogen regulation of fatty acid biosynthesis were found in this strain in comparison with other streptomycetes studied so far. This finding could be explained at the level of regulation of branched-chain amino acid metabolism.
摘要
对阿维菌素产生菌阿维链霉菌C-18在含有不同氮源的化学成分确定的培养基中生长时的脂肪酸组成进行了分析。与迄今研究的其他链霉菌相比，该菌株在脂肪酸生物合成的氮调节方面存在显著差异。这一发现可以在支链氨基酸代谢的调节水平上得到解释。
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