Ge Xiaoxia, Qi Meiling, Li Liang, Hua Fei, Shao Qinglong, Fu Ruonong
The Chinese People's Armed Police Force Academy, Langfang 065000, China.
Se Pu. 2005 May;23(3):305-7.
Heptakis (2,3,6-tri-O-ethyl)-beta-cyclodextrin (CD) (perethylated-beta-CD), heptakis (2,3,6-tri-O-propyl)-beta-CD (perpropylated-beta-CD), heptakis (2,3,6-tri-O-octyl)-beta-CD (peroctylated-beta-CD), and (2,6-di-O-benzyl)-beta-CD were used as stationary phases to prepare columns for gas chromatography by sol-gel technique. The method of coating the columns is similar to the dynamic method and the time required was shortened. Chromatographic characteristics such as column efficiency (around 3000 plates/m), column stability and reproducibility (relative standard deviation below 8.5%) were studied. The columns exhibited good separation ability for disubstituted benzene isomers, especially for xylenes and cresols. In addition, the three peralkylated-beta-CD columns offer better selectivity than the (2,6-di-O-benzyl)-beta-CD column.
七（2,3,6-三-O-乙基）-β-环糊精（CD）（全乙基化-β-CD）、七（2,3,6-三-O-丙基）-β-环糊精（全丙基化-β-CD）、七（2,3,6-三-O-辛基）-β-环糊精（全辛基化-β-CD）和（2,6-二-O-苄基）-β-环糊精被用作固定相，通过溶胶-凝胶技术制备气相色谱柱。柱涂覆方法与动态法相似，所需时间缩短。研究了柱效（约3000塔板/米）、柱稳定性和重现性（相对标准偏差低于8.5%）等色谱特性。这些柱对二取代苯异构体表现出良好的分离能力，特别是对二甲苯和甲酚。此外，三种全烷基化-β-CD柱比（2,6-二-O-苄基）-β-CD柱具有更好的选择性。
