Setubal João C, Moreira Leandro M, da Silva Ana C R
Virginia Bioinformatics Institute and Department of Computer Science, Virginia Polytechnic Institute and State University, Blacksburg, VA 24060-0477, USA.
Curr Opin Microbiol. 2005 Oct;8(5):595-600. doi: 10.1016/j.mib.2005.08.015.
There are now fourteen completed genomes of bacterial phytopathogens, all of which have been generated in the past six years. These genomes come from a phylogenetically diverse set of organisms, and range in size from 870 kb to more than 6Mb. The publication of these annotated genomes has significantly helped our understanding of bacterial plant disease. These genomes have also provided important information about bacterial evolution. Examples of recently completed genomes include: Pseudomonas syringae pv tomato, which is notable for its large repertoire of effector proteins; Leifsonia xyli subsp. xyli, the first Gram-positive bacterial genome to be sequenced; and Phytoplasma asteris, the small genome that lacks important functions previously thought to be essential in a bacterium.
目前已有14种植物病原细菌的基因组测序完成,所有这些都是在过去六年中完成的。这些基因组来自系统发育上多样的一组生物体,大小从870 kb到超过6Mb不等。这些注释基因组的发表极大地帮助了我们对细菌性植物病害的理解。这些基因组还提供了有关细菌进化的重要信息。最近完成测序的基因组实例包括:丁香假单胞菌番茄致病变种,其效应蛋白种类繁多;木糖李氏杆菌木糖亚种,首个完成测序的革兰氏阳性细菌基因组;以及 asteris植原体,其基因组较小,缺少以前认为细菌中必不可少的重要功能。