Pemsel H K, Mahlstedt J, Lange H, Joseph K
Rofo. 1979 Sep;131(3):275-80. doi: 10.1055/s-0029-1231431.
After experimental stenosis of the renal artery of the dog, the isotope nephrogram shows a prolongation of the transit-time, when the renal blood flow is reduced to 40--70%. This finding was most significant in low diuresis (0,05--0,2 ml/min), sporadic in moderate diuresis (0,2--2,0 ml/min), no longer demonstrable in forced diuresis (greater than 2,0 ml/min). The diuretic effect of X-ray contrast medium (70% Na-Meglumin-Jotalamat, 0,5 ml/kg i.v.) normalizes a pathologic ING in low diuresis.
在对狗的肾动脉进行实验性狭窄后，当肾血流量减少到40%-70%时，同位素肾图显示通过时间延长。这一发现在低尿量（0.05-0.2毫升/分钟）时最为显著，在中等尿量（0.2-2.0毫升/分钟）时为偶发情况，在强制利尿（大于2.0毫升/分钟）时则不再明显。X射线造影剂（70%的钠-葡甲胺-碘他拉酸盐，静脉注射0.5毫升/千克）的利尿作用可使低尿量时的病理性肾图正常化。
