Franz Jennifer, Jamieson Denise J, Randall Hugh, Spann Cyril
Department of Gynecology and Obstetrics, Emory University, Atlanta, Georgia 30303, USA.
Infect Dis Obstet Gynecol. 2005 Sep;13(3):167-9. doi: 10.1080/10647440500147901.
To compare the postoperative complication rates after hysterectomy between HIV-infected patients and HIV-uninfected patients.
We conducted a retrospective study of 24 human immunodeficiency virus-infected patients who underwent hysterectomy between January 1, 2000 and April 2, 2003 at Grady Memorial Hospital. Postoperative complications rates among HIV-infected women were compared to those rates among HIV-uninfected women. Data were analyzed t-tests for continuous variables and chi-squared tests for categorical variables.
The HIV-infected women were more likely to report smoking and recreational drug use. In addition, a higher proportion of the HIV-infected women were co-infected with hepatitis, with more than one-quarter of HIV-infected women being hepatitis B or C seropositive. Although the study was limited due to small sample size, no significant differences in complication rates were found among HIV-infected women compared with uninfected women.
As HIV-infected women are living longer, healthier lives we anticipate that increased numbers of HIV-infected women will be undergoing hysterectomy for benign gynecologic conditions. It will be important, therefore, to carefully document any potential differences in operative risks.
比较感染人类免疫缺陷病毒(HIV)的患者与未感染HIV的患者子宫切除术后的并发症发生率。
我们对2000年1月1日至2003年4月2日期间在格雷迪纪念医院接受子宫切除术的24例感染HIV的患者进行了一项回顾性研究。将感染HIV的女性术后并发症发生率与未感染HIV的女性的发生率进行比较。对连续变量的数据采用t检验进行分析,对分类变量的数据采用卡方检验进行分析。
感染HIV的女性更有可能有吸烟和使用消遣性药物的情况。此外,感染HIV的女性中合并感染肝炎的比例更高,超过四分之一的感染HIV的女性乙肝或丙肝血清学呈阳性。尽管由于样本量小,该研究存在局限性,但与未感染的女性相比,感染HIV的女性在并发症发生率方面未发现显著差异。
随着感染HIV的女性寿命延长、生活更健康,我们预计会有越来越多感染HIV的女性因良性妇科疾病接受子宫切除术。因此,仔细记录手术风险中的任何潜在差异将很重要。