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与血清学阴性女性相比,HIV血清学阳性女性子宫切除术后的结局。

Outcomes of hysterectomy in HIV-seropositive women compared to seronegative women.

作者信息

Franz Jennifer, Jamieson Denise J, Randall Hugh, Spann Cyril

机构信息

Department of Gynecology and Obstetrics, Emory University, Atlanta, Georgia 30303, USA.

出版信息

Infect Dis Obstet Gynecol. 2005 Sep;13(3):167-9. doi: 10.1080/10647440500147901.

Abstract

OBJECTIVE

To compare the postoperative complication rates after hysterectomy between HIV-infected patients and HIV-uninfected patients.

STUDY DESIGN

We conducted a retrospective study of 24 human immunodeficiency virus-infected patients who underwent hysterectomy between January 1, 2000 and April 2, 2003 at Grady Memorial Hospital. Postoperative complications rates among HIV-infected women were compared to those rates among HIV-uninfected women. Data were analyzed t-tests for continuous variables and chi-squared tests for categorical variables.

RESULTS

The HIV-infected women were more likely to report smoking and recreational drug use. In addition, a higher proportion of the HIV-infected women were co-infected with hepatitis, with more than one-quarter of HIV-infected women being hepatitis B or C seropositive. Although the study was limited due to small sample size, no significant differences in complication rates were found among HIV-infected women compared with uninfected women.

CONCLUSION

As HIV-infected women are living longer, healthier lives we anticipate that increased numbers of HIV-infected women will be undergoing hysterectomy for benign gynecologic conditions. It will be important, therefore, to carefully document any potential differences in operative risks.

摘要

目的

比较感染人类免疫缺陷病毒(HIV)的患者与未感染HIV的患者子宫切除术后的并发症发生率。

研究设计

我们对2000年1月1日至2003年4月2日期间在格雷迪纪念医院接受子宫切除术的24例感染HIV的患者进行了一项回顾性研究。将感染HIV的女性术后并发症发生率与未感染HIV的女性的发生率进行比较。对连续变量的数据采用t检验进行分析,对分类变量的数据采用卡方检验进行分析。

结果

感染HIV的女性更有可能有吸烟和使用消遣性药物的情况。此外,感染HIV的女性中合并感染肝炎的比例更高,超过四分之一的感染HIV的女性乙肝或丙肝血清学呈阳性。尽管由于样本量小,该研究存在局限性,但与未感染的女性相比,感染HIV的女性在并发症发生率方面未发现显著差异。

结论

随着感染HIV的女性寿命延长、生活更健康,我们预计会有越来越多感染HIV的女性因良性妇科疾病接受子宫切除术。因此,仔细记录手术风险中的任何潜在差异将很重要。

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