Shah K N, Rajadhyaksha S, Shah V S, Wakde M
Department of Pediatrics, Bai Jerbai Wadia Hospital for Children & Institute of Child Health, Parel, Bombay.
Indian J Pediatr. 1992 Jan-Feb;59(1):103-8. doi: 10.1007/BF02760909.
Two cases of alobar holoprosencephaly and two of Aicardi syndrome are reported for their highly specific electroencephalographic (EEG) changes. The asynchronous sharp waves and spikes over the frontal regions with decreasing gradient of potential to the occipital leads were seen in alobar holoprosencephaly while burst suppression pattern with total asynchrony between the two hemispheres was seen in Aicardi syndrome. Even though EEG changes cannot be pathognomic of any abnormality, it is suggested that as in conditions like subacute sclerosing panencephalitis and petitmal epilepsy, so also in alobar holoprosencephaly and Aicardi syndrome, the characteristic features seen on EEG may provide the initial clue to the correct diagnosis.
本文报告了两例无脑叶型前脑无裂畸形和两例艾卡迪综合征患者，因其具有高度特异性的脑电图（EEG）变化。无脑叶型前脑无裂畸形患者可见额区出现不同步的尖波和棘波，且向枕部导联的电位梯度递减；而艾卡迪综合征患者则表现为两半球完全不同步的爆发抑制模式。尽管脑电图变化不能确诊任何异常情况，但有人提出，如同亚急性硬化性全脑炎和失神癫痫等病症一样，无脑叶型前脑无裂畸形和艾卡迪综合征患者脑电图上的特征性表现可能为正确诊断提供初步线索。
