利用漫反射图像对皮肤组织中的局部血液区域进行深度可视化。
Depth visualization of a local blood region in skin tissue by use of diffuse reflectance images.
作者信息
Nishidate Izumi, Aizu Yoshihisa, Mishina Hiromichi
机构信息
Department of Bio-system Engineering, Yamagata University, 4-3-16, Jonan, Yonezawa, Yamagata 992-8510, Japan.
出版信息
Opt Lett. 2005 Aug 15;30(16):2128-30. doi: 10.1364/ol.30.002128.
A simple method is proposed for visualizing the depth distribution of a local blood region in skin tissue by using diffuse reflectance images at two isosbestic wavelengths of hemoglobin, 420 and 585 nm. Monte Carlo simulation of light transport specifies a relation between optical densities and the depth of the region under given concentrations of melanin in the epidermis and blood in the dermis. Phantom and in vivo experiments were performed to show the usefulness of the method.
本文提出了一种简单的方法，通过使用血红蛋白的两个等吸收波长（420和585nm）处的漫反射图像来可视化皮肤组织中局部血液区域的深度分布。光传输的蒙特卡罗模拟确定了在给定的表皮黑色素浓度和真皮血液浓度下，光密度与该区域深度之间的关系。进行了模型实验和体内实验以证明该方法的有效性。
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