Hölzle E, Rowold J, Plewig G
Hautklinik, Heinrich-Heine-Universität Düsseldorf.
Hautarzt. 1992 May;43(5):278-82.
Actinic prurigo is a rare idiopathic photodermatosis, which shares some features with atopic dermatitis, polymorphous light eruption, hydroa vacciniforme and persistent light reaction. It is, however, recognized as a distinct entity. Among American Indians a familial variant is observed. Characteristic features are a chronic course with sustained exacerbations, which are seasonal at first, but later perennial. The disorder may improve in adulthood. The typical clinical features are urticarial plaques a few hours after UV exposure, and a persistent eczematous, prurigo-like rash distributed over skin areas exposed to light but sometimes extending even into photoprotected areas. Therapy is extremely difficult and unrewarding. In the present paper the entity is defined and three typical cases are presented.
光化性痒疹是一种罕见的特发性光皮肤病,它与特应性皮炎、多形性日光疹、种痘样水疱病和持久性光反应有一些共同特征。然而,它被认为是一种独特的疾病。在美国印第安人中观察到一种家族性变体。其特征性表现为病程慢性且持续加重,起初有季节性发作,但后来常年发作。这种疾病在成年期可能会有所改善。典型的临床特征是紫外线照射数小时后出现风团样斑块,以及持续存在的湿疹样、痒疹样皮疹,分布于暴露部位的皮肤,但有时甚至会延伸至光保护区域。治疗极其困难且效果不佳。本文对该疾病进行了定义并介绍了三个典型病例。