Jabbur Nada S, Kraff Colman
Refractive Surgery Center, The Wilmer Eye Institute, The Johns Hopkins University (Jabbur), Baltimore, Maryland, USA.
J Cataract Refract Surg. 2005 Aug;31(8):1493-501. doi: 10.1016/j.jcrs.2004.12.050.
To assess the safety and effectiveness of wavefront guided LASIK surgery using the Visx WaveScan system for correction of low to moderate myopia with astigmatism.
Multicenter study at 6 sites in the United States.
In this prospective nonrandomized clinical trial, treatments were performed at 6 sites in the United States using the WaveScan (CustomVue) guided excimer laser. A total of 351 eyes were enrolled, and 277 eyes were analyzed at 6 months.
At 6 months, 94% of eyes achieved an uncorrected visual acuity (UCVA) of 20/20 or better and 74% achieved a UCVA of 20/16 or better. Sixty-nine percent of eyes had the same or better postoperative UCVA than their preoperative best spectacle-corrected visual acuity (BSCVA). Ninety percent of eyes were within +/-0.5 diopter of intended correction. No eye lost more than 1 line of BSCVA. Total higher-order root-mean square (RMS), coma, and spherical aberration values were stable (P<.05).
The data support the safety and effectiveness of the WaveScan-guided customized laser ablation using the Visx Star S4 system for correction of low to moderate myopia with astigmatism.
评估使用威视WaveScan系统的波前引导准分子原位角膜磨镶术（LASIK）治疗中低度近视合并散光的安全性和有效性。
在美国6个地点进行的多中心研究。
在这项前瞻性非随机临床试验中，在美国6个地点使用WaveScan（CustomVue）引导的准分子激光进行治疗。共纳入351只眼，6个月时对277只眼进行分析。
6个月时，94%的眼睛裸眼视力（UCVA）达到20/20或更好，74%的眼睛UCVA达到20/16或更好。69%的眼睛术后UCVA与术前最佳矫正视力（BSCVA）相同或更好。90%的眼睛矫正度数在预期矫正度数的±0.5屈光度范围内。没有眼睛的BSCVA下降超过1行。总高阶均方根（RMS）、彗差和球差值稳定（P<0.05）。
数据支持使用威视Star S4系统的WaveScan引导的定制激光消融术治疗中低度近视合并散光的安全性和有效性。
