Westhofen M
Hals-, Nasen-, Ohrenklinik, Universitäts-Krankenhauses Eppendorf, Hamburg.
HNO. 1992 May;40(5):176-80.
Surgical treatment of Meniere's disease is indicated in patients with severe attacks who have failed drug therapy. A decision between a conservative or destructive procedure demands firstly exclusion of patients with non-otogenic diseases, bilateral disease or complete unilateral loss of function, and secondly assessment of the laterality of the disease, of residual labyrinthic function and of vestibular compensation. A total of 185 patients with Meniere's disease were investigated. All of them had a history and clinical signs that indicated surgery. Canal function, otolith responses and vestibular compensation were examined, in addition to routine preoperative tests as recommended by the Committee on Hearing and Equilibrium of the American Academy of Ophthalmology and Otolaryngology. Of the 185 patients 22% had findings that contraindicated surgery, 4% suffered from Meniere's disease in the opposite ear, 6% showed no signs of vestibular compensation and 12% had dead labyrinths on the side of the cochlear disease. No caloric response was elicited from the labyrinth by thermal bilateral testing in 25% of the 185 patients. In patients who were thought to have dead labyrinths based on routine caloric tests, residual canal function was detected by means of 20 degrees C stimulation in the prone and supine position. Without extensive vestibular testing the indications for surgical treatment of Meniere's disease will be incorrect in 47% of patients.
对于药物治疗无效的重度梅尼埃病发作患者,需进行手术治疗。在决定采用保守性或破坏性手术时,首先要排除非耳源性疾病、双侧患病或单侧功能完全丧失的患者,其次要评估疾病的患侧性、残余迷路功能和前庭代偿情况。共对185例梅尼埃病患者进行了调查。他们均有提示手术治疗的病史和临床体征。除了美国眼耳鼻喉科协会听力与平衡委员会推荐的常规术前检查外,还对管功能、耳石反应和前庭代偿进行了检查。185例患者中,22%有手术禁忌证,4%对侧耳患有梅尼埃病,6%无前庭代偿迹象,12%患侧耳蜗疾病伴有迷路坏死。185例患者中25%经双侧冷热试验未引出迷路的冷热反应。对于根据常规冷热试验被认为迷路坏死的患者,通过在俯卧位和仰卧位进行20摄氏度刺激检测残余管功能。若不进行广泛的前庭检查,47%的梅尼埃病手术治疗适应证将判断错误。