Gootman P M, Gandhi M R, Coren C V, Kaplan N M, Pisana F M, Buckley B J, Armour J A, Gootman N
Department of Physiology, State University of New York, Brooklyn 11203.
J Auton Nerv Syst. 1992 May 15;38(3):191-200. doi: 10.1016/0165-1838(92)90030-k.
Stimulation with bipolar electrodes of specific loci in stellate ganglia elicited in anesthetized piglets, 1-4 weeks of age, alterations in cardiac function and aortic pressure. Responses were also elicited by chemical stimulation in specific loci of these ganglia. The probability of eliciting a cardiovascular response by stimulating loci in a stellate ganglion increased with increasing postnatal age. For instance, no responses were elicited when loci in the left stellate ganglia of 1-week-old piglets were stimulated. Significant heart rate responses were obtained only when loci in right stellate ganglia were stimulated. The number of ganglionic loci from which cardiovascular responses were obtained increased with increasing postnatal age. It is concluded that the capacity of stellate ganglion neurons to modulate the cardiovascular system matures during the first four weeks of life, heart rate being modulated primarily by neurons in the right stellate ganglion and inotropism by neurons in both stellate ganglia.
用双极电极刺激1至4周龄麻醉仔猪星状神经节的特定部位，可引起心脏功能和主动脉压力的改变。在这些神经节的特定部位进行化学刺激也可引发反应。随着出生后年龄的增加，刺激星状神经节部位引发心血管反应的概率增加。例如，刺激1周龄仔猪左侧星状神经节的部位时未引发反应。仅在刺激右侧星状神经节的部位时才获得显著的心率反应。随着出生后年龄的增加，获得心血管反应的神经节部位数量增加。得出的结论是，星状神经节神经元调节心血管系统的能力在生命的前四周内成熟，心率主要由右侧星状神经节中的神经元调节，而心肌收缩力则由双侧星状神经节中的神经元调节。
