Ulmer W T
Med Klin. 1979 Oct 19;74(42):1548-52.
Fenoterol-Ipratropiumbromid dosage aerosol (IK 6) showed in acute experiments on patients with chronic obstructive disease optimal bronchodilatation. In this mixture of Fenoterol and Ipratropiumbromid only 50% of the optimal dosage of the beta 2-stimulator is present. This minimizes the side-effects and increases the therapeutic range. Still the bronchodilatation is optimal. 92 patients were treated with this mixture for between 1 and 160 months. No side-effects were seen. The optimal bronchodilatatoric effect was always present.
非诺特罗-异丙托溴铵剂量气雾剂(IK 6)在慢性阻塞性疾病患者的急性实验中显示出最佳的支气管扩张作用。在这种非诺特罗和异丙托溴铵的混合物中,仅含有β2激动剂最佳剂量的50%。这将副作用降至最低并扩大了治疗范围。支气管扩张效果仍然最佳。92名患者使用这种混合物治疗了1至160个月。未观察到副作用。始终存在最佳的支气管扩张作用。