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补肾壮骨合剂治疗原发性骨质疏松96例临床观察

Clinical observation on 96 cases of primary osteoporosis treated with kidney-tonifying and bone-strengthening mixture.

作者信息

Mingyue Wang, Ling Gong, Bei Xia, Junqing Cao, Peiqing Zhou, Jie Hu

机构信息

Xuanwu Hospital Affiliated to Capital Medical University, Beijing 100053, China.

出版信息

J Tradit Chin Med. 2005 Jun;25(2):132-6.

PMID:16136945
Abstract

OBJECTIVE

To objectively evaluate the therapeutic effect and safety of Mixture for Nourishing Kidney and Strengthening Bone.

METHOD

Among 160 cases of osteoporosis under clinical observation, 96 patients in the treatment group were treated with Mixture for Nourishing Kidney and Strengthening Bone, 32 patients in the control group were given Shen Gu Capsule and 32 patients in the blank group were given no drug in half a year. Observation and determination were conducted on bone mineral density (BMD), clinical symptoms, bone gla protein (BGP), pyridinoline (PYD), estradiol (E2), testosterone (T), blood urea nitrogen (BUN), transaminase and routine test on blood and urine.

RESULT

The comprehensive effect in the treatment group was remarkably superior to that in the control group.

CONCLUSION

The safe and reliable Chinese drug can enhance BMD, promote osteogenesis and inhibit bone absorption, hence treating osteoporosis with marked effect.

摘要

目的

客观评价补肾壮骨合剂的治疗效果及安全性。

方法

在160例临床观察的骨质疏松症患者中,治疗组96例服用补肾壮骨合剂,对照组32例服用肾骨胶囊,空白组32例半年未用药。对骨密度(BMD)、临床症状、骨钙素(BGP)、吡啶啉(PYD)、雌二醇(E2)、睾酮(T)、血尿素氮(BUN)、转氨酶以及血尿常规进行观察和测定。

结果

治疗组综合效果明显优于对照组。

结论

该中药安全可靠,能提高骨密度,促进成骨,抑制骨吸收,治疗骨质疏松症效果显著。

相似文献

1
Clinical observation on 96 cases of primary osteoporosis treated with kidney-tonifying and bone-strengthening mixture.补肾壮骨合剂治疗原发性骨质疏松96例临床观察
J Tradit Chin Med. 2005 Jun;25(2):132-6.
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Clinical observation on treatment with the kidney-tonifying prescription in 25 cases of postmenopausal osteoporosis.补肾方剂治疗25例绝经后骨质疏松症的临床观察
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引用本文的文献

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Treatment effect of extract on postmenopausal osteoporosis .提取物对绝经后骨质疏松症的治疗效果。
Exp Ther Med. 2014 Jun;7(6):1687-1690. doi: 10.3892/etm.2014.1661. Epub 2014 Apr 2.