[阻塞性睡眠呼吸暂停低通气综合征对QTc间期的影响]
[Influence of obstructive sleep apnea-hypopnea syndrome on the QTc interval].
作者信息
Luo Ying-Quan, Yang Yu, Yu Shao-Fen
机构信息
Department of Geriatrics, Second Xiangya Hospital, Central South University, Changsha 410011, China.
出版信息
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2004 Feb;29(1):97-8.
OBJECTIVE
To investigate the influence of obstructive sleep apnea-hypopnea syndrome (OSAHS) on the QTc interval.
METHODS
By the polysomnograph,98 patients were divided into an obstructive sleep apnea-hypopnea syndrome group and a control group. We tested their 24 hour DCG and observed the difference of the heart rate,QT interval and QTc interval at the same time.
RESULTS
We compared the heart rate (76 +/- 10 bt/min), QT interval (366 +/- 30 ms), and QTc interval (404 +/- 45 ms) with those of the control group (73 +/- 96 bt/min, 342 +/- 31 ms, 374 +/- 30 ms, respectively). The QT interval and QTc interval significantly differred (P < 0.05).
CONCLUSION
The QT interval and QTc interval in the OSAHS group has been prolonged, suggesting OSAHS might be a high risk factor in arrhythmia and sudden death.
目的
探讨阻塞性睡眠呼吸暂停低通气综合征（OSAHS）对QTc间期的影响。
方法
通过多导睡眠图，将98例患者分为阻塞性睡眠呼吸暂停低通气综合征组和对照组。检测两组患者的24小时动态心电图（DCG），同时观察心率、QT间期及QTc间期的差异。
结果
将心率（76±10次/分钟）、QT间期（366±30毫秒）和QTc间期（404±45毫秒）与对照组（分别为73±96次/分钟、342±31毫秒、374±30毫秒）进行比较。QT间期和QTc间期有显著差异（P<0.05）。
结论
OSAHS组的QT间期和QTc间期延长，提示OSAHS可能是心律失常和猝死的高危因素。
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