Munch Inger Christine, Larsen Michael
H:S Frederiksberg Hospital, Øjenklinikken Amtssygehuset i Herlev, Øjenafdelingen, Frederiksberg.
Ugeskr Laeger. 2005 Aug 29;167(35):3269-73.
The ocular ischemic syndrome is caused by severely reduced ocular perfusion, usually secondary to carotid artery stenosis. Because of the low perfusion pressure, anterior chamber rubeosis does not invariably lead to increased intraocular pressure. The characteristic ocular pain is unrelated to the intraocular pressure. Patients adapt slowly to increasing light intensity (bright light amaurosis fugax). Retinal hemorrhages often lead to the mistaken assumption that the patient has diabetic retinopathy, especially when the patient has diabetes. A definite diagnosis is made by the demonstration of severely decreased ocular perfusion pressure. Supporting evidence is delayed filling on fundus fluorescein angiography in a patient with high-grade carotid artery stenosis. The majority of affected eyes lose vision for finger counting within one year. No treatment of documented value is available. Patients without neovascularization of the anterior chamber angle may occasionally experience improved vision after carotid surgery.
眼部缺血综合征由眼部灌注严重减少引起，通常继发于颈动脉狭窄。由于灌注压低，前房虹膜红变并不一定会导致眼压升高。其特征性眼痛与眼压无关。患者对逐渐增加的光强度适应缓慢（强光性一过性黑矇）。视网膜出血常导致错误地认为患者患有糖尿病性视网膜病变，尤其是当患者患有糖尿病时。通过证实眼部灌注压严重降低可做出明确诊断。支持性证据是在患有重度颈动脉狭窄的患者中，眼底荧光血管造影显示充盈延迟。大多数受影响的眼睛在一年内视力会下降到只能数指。目前尚无经证实有效的治疗方法。无前房角新生血管形成的患者在颈动脉手术后偶尔视力会有所改善。
