重型β地中海贫血患者的妊娠管理

Management of pregnancy in a patient with beta thalassaemia major.

作者信息

Butwick A, Findley I, Wonke B

机构信息

Department of Anaesthesia, St. George's Hospital, London, UK.

出版信息

Int J Obstet Anesth. 2005 Oct;14(4):351-4. doi: 10.1016/j.ijoa.2005.02.002.

DOI:10.1016/j.ijoa.2005.02.002

PMID:16140004

Abstract

beta thalassaemia is one of the world's most wide-spread monogenetic disorders. Advances in the management of beta thalassaemia major by extensive blood transfusions and chelation therapy have improved survival of patients into adult life. Due to the prolonged life expectancy and improvements in quality of life, pregnancy has now become an important issue for patients and clinicians. We report a case of a pregnant patient with beta thalassaemia major who underwent a successful caesarean section under spinal anaesthesia. The multidisciplinary approach to management of beta thalassaemia major and pregnancy is discussed.

摘要

β地中海贫血是世界上最广泛传播的单基因疾病之一。通过广泛输血和螯合疗法对重型β地中海贫血进行管理的进展，提高了患者成年后的生存率。由于预期寿命延长和生活质量改善，怀孕现在已成为患者和临床医生面临的一个重要问题。我们报告一例重型β地中海贫血孕妇，在脊髓麻醉下成功进行剖宫产的病例。并讨论了重型β地中海贫血和妊娠管理的多学科方法。