Healy Kelly A, Hood Nedra, Ogan Kenneth
Department of Urology, Emory University School of Medicine, Atlanta, Georgia, USA.
Urology. 2005 Sep;66(3):658. doi: 10.1016/j.urology.2005.03.049.
Renal cell carcinoma is relatively common in patients with von Hippel-Lindau disease, yet characteristically follows a less aggressive course compared with sporadic renal cell carcinoma. We report on 2 patients with von Hippel-Lindau disease and atypically aggressive renal tumors. In these patients, more rigorous screening guidelines may help to identify the more aggressive variants.
肾细胞癌在冯·希佩尔-林道病患者中相对常见,但与散发性肾细胞癌相比,其特征是病程侵袭性较小。我们报告了2例患有冯·希佩尔-林道病且患有非典型侵袭性肾肿瘤的患者。在这些患者中,更严格的筛查指南可能有助于识别侵袭性更强的变异体。