Knyshov G V, Furkalo S N, Ursulenko V I, Vykhovaniuk I V, Berestovenko V S
Kardiologiia. 1992 Jan;32(1):13-5.
To examine the time course of changes in the coronary arteries in patients with coronary heart disease after aortocoronary bypass (ACB), the authors studied 2 groups of patients: (1) 23 who had conservative treatment and (2) 23 who were selected for ACB. Repeated angiography was performed 14.6 +/- 2.5 months after the initiation of the study. Following ACB, changes in lesions were observed in 17 coronary artery segments in 39.1% of the patients. Grafted artery stenoses largely proximal to the site of transplantation became progressive. There was a relationship between the changes in coronary arteries to graft patency. In Group 1, the time course of coronary atherosclerosis was found in 8 segments in 26% of the cases. Atherosclerosis progressed in all artery segments virtually in a steady way. Application of vein grafts may change intracoronary hemodynamics, creating conditions for more rapid and common progression of coronary artery lesions.
为研究冠心病患者在主动脉冠状动脉旁路移植术(ACB)后冠状动脉变化的时间进程,作者对两组患者进行了研究:(1)23例接受保守治疗的患者和(2)23例被选作ACB的患者。在研究开始14.6±2.5个月后进行了重复血管造影。ACB后,39.1%的患者在17个冠状动脉节段观察到病变变化。移植动脉在移植部位近端的狭窄大多呈进行性发展。冠状动脉变化与移植血管通畅之间存在关联。在第1组中,26%的病例在8个节段发现了冠状动脉粥样硬化的时间进程。所有动脉节段的动脉粥样硬化几乎都以稳定的方式进展。应用静脉移植物可能会改变冠状动脉内的血流动力学,为冠状动脉病变更快速和常见的进展创造条件。