Alberta Lauren, Sweeney Susan M, Wiss Karen
Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.
Pediatrics. 2005 Sep;116(3):e450-2. doi: 10.1542/peds.2004-2066.
Diaper dermatitis is a common problem in outpatient pediatric office settings. Although most diaper rashes represent a form of contact dermatitis in response to irritants in the diaper environment, other rashes may be the result of an allergen in the diaper. On the basis of clinical examination results for 5 patients and patch testing results for 2 patients, we suspect that the patients demonstrated allergic contact dermatitis in response to the various blue, pink, and green dyes in diapers. Although topically administered corticosteroids are useful in the treatment regimen, the preferred treatment for allergic contact dermatitis in the diaper area is the use of dye-free diapers for allergen avoidance. Patch testing may also be valuable in identifying the allergen, because allergen avoidance is the key to prevention of recurrent disease.
尿布皮炎是儿科门诊常见的问题。尽管大多数尿布疹是对尿布环境中的刺激物产生的一种接触性皮炎，但其他皮疹可能是由尿布中的过敏原引起的。根据5例患者的临床检查结果和2例患者的斑贴试验结果，我们怀疑这些患者表现出对尿布中各种蓝色、粉色和绿色染料的过敏性接触性皮炎。虽然局部使用皮质类固醇在治疗方案中是有用的，但尿布区域过敏性接触性皮炎的首选治疗方法是使用无染料尿布以避免接触过敏原。斑贴试验在识别过敏原方面也可能有价值，因为避免接触过敏原是预防疾病复发的关键。
