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山羊体内无抗凝治疗的机械心脏瓣膜的五年评估

The five-year evaluation of a mechanical heart valve without anticoagulation in goats.

作者信息

Björk V O, Kaminsky D B

机构信息

Pathology Department, Eisenhower Medical Center, Rancho Mirage, Calif.

出版信息

J Thorac Cardiovasc Surg. 1992 Jul;104(1):22-5.

PMID:1614211
Abstract

Two 5-year observations of goats with microporous surfaced Björk-Shiley Monostrut mitral heart valves without anticoagulation show the important point that one went through four the other two normal pregnancies with delivery of fourteen kids. Furthermore, the local findings on the valves suggest that the porous surface should be used only to invite a thin, endothelialized neointima over a preferably carbon-coated suture ring to continue over the groove and to the adjacent part of the valve flange. The vertical or central part of the ring and the struts, in the control material with a polished surface, have never been the origin of a thrombus and should therefore be polished.

摘要

对两只植入微孔表面的 Björk-Shiley Monostrut 二尖瓣心脏瓣膜且未进行抗凝治疗的山羊进行了为期 5 年的观察,结果显示了一个重要情况:其中一只山羊经历了四次正常妊娠并产下 14 只小羊,另一只山羊情况正常。此外,瓣膜的局部观察结果表明,多孔表面仅应在最好是碳涂层缝合环上用于促使形成一层薄的、内皮化的新生内膜,该新生内膜要延续至凹槽并覆盖瓣膜凸缘的相邻部分。在具有光滑表面的对照材料中,环和支柱的垂直或中央部分从未成为血栓的起源,因此应进行抛光处理。

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