Weiss M E
Division of Allergy, University of Washington School of Medicine, Seattle.
Med Clin North Am. 1992 Jul;76(4):857-82. doi: 10.1016/s0025-7125(16)30329-7.
Although allergic drug reactions are just one type of adverse reaction to medications, they are clinically very important because of the morbidity and mortality they cause. An ever-expanding pharmacopeia increases the potential for allergic drug reactions. An understanding of the types of allergic drug reactions, their immunopathologic mechanisms, and the most likely medications involved; an approach to determine the drug responsible for the reaction; and ways to prevent future allergic drug reactions are important features in minimizing patient morbidity.
尽管药物过敏反应只是药物不良反应的一种类型，但因其所导致的发病率和死亡率，在临床上非常重要。不断扩充的药典增加了药物过敏反应的可能性。了解药物过敏反应的类型、免疫病理机制以及最可能涉及的药物；确定引起反应的药物的方法；以及预防未来药物过敏反应的方法，是将患者发病率降至最低的重要因素。
