[环状软骨上部分喉切除术治疗喉癌]

[Supracricoid partial laryngectomy for the treatment of laryngeal cancer].

作者信息

Tang Ping-zhang, Tang Ping-zhang, Qi Yong-fa, Xu Zhen-gang, Wu Yao-huang

机构信息

Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China.

出版信息

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2005 Jun;40(6):423-6.

PMID:16144335

Abstract

OBJECTIVE

To evaluate the oncological and functional outcomes in patients undergoing supracricoid partial laryngectomy (SCPL).

METHODS

Forty-three cases underwent supracricoid partial laryngectomy with functional reconstruction in stage T1b-T4. In these cases, 16 were supraglottic cancers, 21 were glottic cancers, and 2 were subglottic cancers. Three types of supracricoid partial laryngectomy (cricohyoidopexy CHP, cricohyoidoepiglottopexy CHEP and tracheocricohyoidoepiglottopexy TCHEP) were employed accordingly.

RESULTS

The 3- and 5-year accumulative survival rates were 90.7% and 83.7% respectively (Kaplan-Meier method). Median follow-up time was 57 months. Decannulation rate was 95.3% (41/43) in those. The mean time of decannulation was 14 days in patients preserved both cricoarytenoid units and 43 days in those only preserved one cricoarytenoid unit. The removal of epiglottis increased the risk of aspiration and prolonged time of decannulation (P < 0.05).

CONCLUSIONS

Supracricoid partial laryngectomy for selected laryngeal cancer is feasible. The patients can gain satisfied survival rate and quality of life.

摘要

目的

评估接受环状软骨上部分喉切除术（SCPL）患者的肿瘤学及功能预后。

方法

43例T1b - T4期患者接受了环状软骨上部分喉切除术及功能重建。其中，声门上癌16例，声门癌21例，声门下癌2例。相应采用了三种类型的环状软骨上部分喉切除术（环舌骨固定术CHP、环舌会厌固定术CHEP和气管环舌会厌固定术TCHEP）。

结果

3年和5年累积生存率分别为90.7%和83.7%（Kaplan - Meier法）。中位随访时间为57个月。这些患者的拔管率为95.3%（41/43）。保留双侧环杓单位的患者平均拔管时间为14天，仅保留单侧环杓单位的患者平均拔管时间为43天。会厌切除增加了误吸风险并延长了拔管时间（P < 0.05）。