Nolin Kristine A, Ahn Richard W, Toste F Dean
Department of Chemistry, University of California, Berkeley, California 94720, USA.
J Am Chem Soc. 2005 Sep 14;127(36):12462-3. doi: 10.1021/ja050831a.
An air- and moisture-tolerant enantioselective hydrosilylation of N-phosphinyl imines employing a chiral Re(V)-oxo complex as a catalyst is described. The chiral catalyst is a cyanobis(oxazoline) (CNbox)-ligated rhenium-oxo complex of the general formula (CNbox)Re(O)Cl2(OPPh3). Using this catalyst, a wide range of aromatic imines (including cyclic, acyclic, and heteroaromatic), alpha-iminoesters, and alpha,beta-unsaturated imines are reduced with good to excellent enantioselectivities.
描述了一种使用手性铼（V）-氧配合物作为催化剂，对N-磷酰基亚胺进行空气和水分耐受的对映选择性硅氢化反应。手性催化剂是通式为(CNbox)Re(O)Cl2(OPPh3)的氰基双恶唑啉（CNbox）连接的铼-氧配合物。使用该催化剂，多种芳香族亚胺（包括环状、非环状和杂芳香族）、α-亚胺酯和α,β-不饱和亚胺以良好至优异的对映选择性被还原。
