香豆素连接的杯[4]吡咯：一种受阳离子和阴离子结合调节的荧光阴离子受体。

Coumarin-strapped calix[4]pyrrole: a fluorogenic anion receptor modulated by cation and anion binding.

作者信息

Miyaji Hidekazu, Kim Hae-Kyung, Sim Eun-Kyung, Lee Chang-Kiu, Cho Won-Seob, Sessler Jonathan L, Lee Chang-Hee

机构信息

Department of Chemistry and Institute of Basic Science, Kangwon National University, Chun-Chon 200-701 Korea.

出版信息

J Am Chem Soc. 2005 Sep 14;127(36):12510-2. doi: 10.1021/ja053612y.

DOI:10.1021/ja053612y

PMID:16144397

Abstract

A new strapped calix[4]pyrrole containing a fluorophore as part of the strap has been synthesized and characterized. Association constants with various anions have been determined using both fluorescence titration and isothermal titrations calorimetry (ITC). The two sets of association constants were found to be in good agreement with one another. The fluorescence emission properties of this new receptor could be controlled by addition of Na+ (or H2O) and anions. However, the fluorescence quenching by anions is only observed in the presence of Na+ (or H2O). All the experimental evidence is consistent with the notion that independent PET processes are modulated by separate cation and anion recognition events. As such, this system operates as an elementary logic gate wherein anion and cation concentrations serve as the input and fluorescence intensity changes provide the output.

摘要

一种新型的带有作为链带一部分的荧光团的束缚杯[4]吡咯已被合成并表征。使用荧光滴定和等温滴定量热法（ITC）测定了与各种阴离子的缔合常数。发现这两组缔合常数彼此吻合良好。这种新型受体的荧光发射特性可通过加入Na⁺（或H₂O）和阴离子来控制。然而，只有在存在Na⁺（或H₂O）的情况下才观察到阴离子引起的荧光猝灭。所有实验证据都与独立的光诱导电子转移（PET）过程由单独的阳离子和阴离子识别事件调节这一观点一致。因此，该系统作为一个基本逻辑门运行，其中阴离子和阳离子浓度作为输入，荧光强度变化作为输出。