Younis G, Sawaya R
Department of Neurosurgery, University of Texas, M. D. Anderson Cancer Center, Houston.
Neurosurgery. 1992 Jun;30(6):932-5. doi: 10.1227/00006123-199206000-00022.
Malignancy is rare in intracranial meningiomas. Although the topic is widely discussed, there is little agreement in the literature as to the histological and radiological features that warrant the diagnosis of malignant meningioma. Three patients are described who had soft-tissue masses and underlying osteolytic lesions on computed tomography. All three patients also had a large intracranial component that proved to be a malignant meningioma. Rarely do meningiomas have all three of these features. We propose that a meningioma causing osteolysis and soft-tissue extension should be considered malignant until proven otherwise.
恶性颅内脑膜瘤很罕见。尽管这个话题被广泛讨论,但对于诊断恶性脑膜瘤所需的组织学和放射学特征,文献中几乎没有一致的看法。本文描述了三名患者,他们在计算机断层扫描上有软组织肿块和潜在的溶骨性病变。所有三名患者还都有一个大的颅内成分,经证实是恶性脑膜瘤。脑膜瘤很少同时具备这三个特征。我们建议,在没有其他证据的情况下,引起骨质溶解和软组织扩展的脑膜瘤应被视为恶性。