Beverina Luca, Abbotto Alessandro, Landenna Mirko, Cerminara Michele, Tubino Riccardo, Meinardi Francesco, Bradamante Silvia, Pagani Giorgio A
Department of Materials Science and INSTM, University of Milano-Bicocca, Via Cozzi 53, I-20125 Milano, Italy.
Org Lett. 2005 Sep 15;7(19):4257-60. doi: 10.1021/ol0516871.
[graph: see text] Condensation of squaric acid with a number of differently substituted 2-pyrrolyl derivatives afforded three new classes of squaraines. Their sharp and intense absorption bands in the biological window (700-900 nm), inherent singlet oxygen generation capabilities, together with proper functionalization allowing good water solubility make them suitable candidates as new non-porphyrinic singlet oxygen photosensitizers for photodynamic therapy (PDT).
