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[92例慢性阻塞性肺疾病患者动脉血气图面积与酸碱平衡紊乱的相关性]

[Correlation between the area of arterial blood gases graph and the acid-base disturbance in 92 cases with chronic obstructive pulmonary disease].

作者信息

Chen Jian-rong, Cai Ying-yun, Xie Xiao-qian, Chen Jia-yi, Cao Yang, Li Min, Tao Yi-jiang

机构信息

The Second Affiliated Hospital of Nantong Medical College, Nantong 226001, Jiangsu, China.

出版信息

Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2005 Sep;17(9):527-9.

Abstract

OBJECTIVE

To study the correlation between the area of arterial blood gases graph (ABGG) and the acid-base disturbance (ABD).

METHODS

Using the software developed by ourselves, the results of arterial blood gases and concomitant electrolyte (K(+), Na(+), Cl(-), HCO(3)(-)) determination in 313 episodes were analyzed in 92 cases with chronic obstructive pulmonary diseases (COPD) during hospitalization, and the correlation was studied.

RESULTS

(1)On admission, among 92 cases, in 9 cases the results of blood gas analysis were in the area of compensated ventilation and deranged gas exchange (area IV), in 82 cases the results were in the area of insufficient ventilation and deranged gas exchange (area V), and 1 case in the area of excessive ventilation and deranged gas exchange (area VI). There were 8 types of the ABDs, and respiratory acidosis (RAC)+metabolic alkalosis (MAL), RAC, RAC+metabolic acidosis (MAC) with increase in anion gap (AG) ranked in above order. (2)At the time of discharge, in 2 cases the distribution of ABGG was in the normal area (area I), 5 cases in the area IV, 20 cases in the area V, and 1 case in the area VI. There were 5 types of the ABDs. RAC+MAL and RAC ranked in the first two positions. (3)During hospitalization, the correlations between the area of ABGG and ABD in 313 episodes were as follows: ABD normal and MAC of AG increased in the area I; ABD normal and MAL, MAC with AG increased, RAC+MAC, respiratory alkalosis (RAL)+MAL, MAL+MAC of AG increased, RAC+MAL+MAC of AG increased and RAL+MAL+MAC of AG increased in the area IV; RAC, MAL, RAC+MAL, RAC+MAC of AG increased, MAL+MAC of AG increased, and RAC+MAL+MAC of AG increased in the area V; MAC of AG increased, RAC+MAC, RAL+MAL, MAL+MAC of AG increased, and RAL+MAL+MAC of AG increased in the area VI. No ABD occurred in the areas II and III.

CONCLUSION

The correlation between ABGG and ABD can be analyzed easily and quickly and the accuracy of results is ensured by using the software.

摘要

目的

研究动脉血气图(ABGG)面积与酸碱平衡紊乱(ABD)之间的相关性。

方法

应用自行开发的软件,对92例慢性阻塞性肺疾病(COPD)患者住院期间313次动脉血气及同步电解质(K⁺、Na⁺、Cl⁻、HCO₃⁻)测定结果进行分析,并研究其相关性。

结果

(1)入院时,92例患者中,血气分析结果处于代偿性通气和气体交换紊乱区域(IV区)的有9例,处于通气不足和气体交换紊乱区域(V区)的有82例,处于通气过度和气体交换紊乱区域(VI区)的有1例。ABD有8种类型,呼吸性酸中毒(RAC)+代谢性碱中毒(MAL)、RAC、阴离子间隙(AG)升高的RAC+代谢性酸中毒(MAC)依次位列上述顺序。(2)出院时,ABGG分布于正常区域(I区)的有2例,IV区的有5例,V区的有20例,VI区的有1例。ABD有5种类型。RAC+MAL和RAC位列前两位。(3)住院期间,313次ABGG面积与ABD的相关性如下:I区为ABD正常和AG升高的MAC;IV区为ABD正常和MAL、AG升高的MAC、RAC+MAC、呼吸性碱中毒(RAL)+MAL、AG升高的MAL+MAC、AG升高的RAC+MAL+MAC及AG升高的RAL+MAL+MAC;V区为RAC、MAL、RAC+MAL、AG升高的RAC+MAC、AG升高的MAL+MAC及AG升高的RAC+MAL+MAC;VI区为AG升高的MAC、RAC+MAC、RAL+MAL、AG升高的MAL+MAC及AG升高的RAL+MAL+MAC。II区和III区未发生ABD。

结论

应用该软件可简便快速地分析ABGG与ABD之间的相关性,并确保结果的准确性。

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