Sezaki T, Hujita M, Oka A, Tanaka T
Acta Med Okayama. 1979 Dec;33(6):451-4.
In the six cases of tumor-forming type as described in the part I of this series, the estimated ages at disease onset ranged from 55 to 82 years old. Tumor-forming sites consisted of three cases each in skull and ribs, and one each in pelvis and palate. Bone x-rays revealed usually larger punched-out lesions adjacent to smaller punched-out lesions with tumor formation corresponding to the larger lesion. Plasma cells averaged 5.8% in myelogram, and monoclonal immunoglobulin consisted all of IgG. Clinical stages were in IA in four patients vs. IIA in two, and single or combined chemotherapy worked well on all the patients. A comparative study on decrease of monoclonal immunoglobulin value against chemotherapy between tumor-forming and non-tumor-forming types was made. The uniqueness of the tumor-forming type was emphasized to arouse attention to appropriate therapeutic measures for these patients.
在本系列第一部分所述的6例肿瘤形成型病例中，疾病发病时的估计年龄在55至82岁之间。肿瘤形成部位包括颅骨和肋骨各3例，骨盆和腭部各1例。骨X光片通常显示，在较大的筛孔状病变附近有较小的筛孔状病变，肿瘤形成与较大病变相对应。骨髓象中浆细胞平均占5.8%，单克隆免疫球蛋白均为IgG。临床分期为IA期4例，IIA期2例，所有患者接受单药或联合化疗效果良好。对肿瘤形成型和非肿瘤形成型患者化疗后单克隆免疫球蛋白值下降情况进行了比较研究。强调了肿瘤形成型的独特性，以引起对这些患者适当治疗措施的关注。
