Háber A, Nagy J, Deák G, Süle T
Pécsi Orvostudományi Egyetem, II. sz. Belgyógyászati Klinika, Pécs.
Orv Hetil. 1992 Jun 28;133(26):1631-5.
A single case of IgA nephropathy with a concomitant tubulointerstitial nephritis, developing during a long-term phenytoin therapy is reported. The prolonged phenytoin therapy did neither prevent the transitional increases of serum IgA level nor ward off deterioration of the histological alterations. This case suggests that acute tubulointerstitial nephritis may have played a role in the mesangial trapping of IgA immunocomplexes.
报告了1例在长期苯妥英治疗期间发生的伴有肾小管间质性肾炎的IgA肾病。长期苯妥英治疗既未能阻止血清IgA水平的过渡性升高，也未能防止组织学改变的恶化。该病例提示急性肾小管间质性肾炎可能在IgA免疫复合物的系膜沉积中起作用。
