Tanemoto Kazuo
Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Kawasaki Medical School, Okayama, Japan.
Ann Thorac Cardiovasc Surg. 2005 Aug;11(4):228-31.
In cases of old myocardial infarction, the presence of mitral valve regurgitation is one of the predicting factors of long-term prognosis. The mechanism of ischemic mitral regurgitation consists of mitral annular dilatation, left ventricular (LV) dilatation followed by tethering of the mitral valve, etc. Since long-term prognosis of the patients in whom the degree of mitral valve regurgitation is 2+ or more is typically poor, the mitral valve procedure should be considered at the time of coronary artery bypass grafting (CABG) or more. In this type of surgery, the treatment essentially involves the use of an artificial ring implantation as the basic technique. In the chronic stage, a significant degree of mitral regurgitation persists in approximately 20% of the cases if they have been treated by ring annuloplasty alone. Additional surgical procedures that reduce or eradicate the tethering are essential for the control of the regurgitation completely in cases with strong tethering. We recently employed two new surgical techniques, namely, cutting the secondary chordae to the anterior mitral valve leaflet and the anterior and posterior papillary muscle reapproximation. The surgical results of the acute phase appear to be promising; however, the long-term results of such new methods are yet to be determined. If the mitral valve regurgitation cannot be controlled even by various operative techniques of mitral valve repair, mitral valve replacement should be considered. This is because the long-term survival rate of the suboptimal repair surgical patients is lower when compared with that of mitral valve replacement patients.
在陈旧性心肌梗死病例中,二尖瓣反流的存在是长期预后的预测因素之一。缺血性二尖瓣反流的机制包括二尖瓣环扩张、左心室(LV)扩张继而二尖瓣瓣叶受限等。由于二尖瓣反流程度为2+及以上的患者长期预后通常较差,在冠状动脉旁路移植术(CABG)时或更应考虑二尖瓣手术。在这类手术中,治疗主要涉及使用人工瓣环植入作为基本技术。在慢性期,如果仅通过瓣环成形术治疗,约20%的病例会持续存在显著程度的二尖瓣反流。对于瓣叶受限严重的病例,采取减少或消除瓣叶受限的额外手术操作对于完全控制反流至关重要。我们最近采用了两种新的手术技术,即切断二尖瓣前叶的二级腱索以及前后乳头肌重新对合。急性期的手术结果似乎很有前景;然而,此类新方法的长期结果尚待确定。如果即使通过各种二尖瓣修复手术技术仍无法控制二尖瓣反流,则应考虑二尖瓣置换。这是因为与二尖瓣置换患者相比,二尖瓣修复手术效果欠佳的患者长期生存率较低。