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胃肠道扩散系统(GDS)的研究:阿拉伯胶对游离醋酸纤维素膜机械性能和化学性能的影响。

Study of the gastrointestinal diffusion system (GDS): influence of acacia gum on mechanical and chemical properties in free cellulose acetate films.

作者信息

Mahieux P, Arnaud P, Chaumeil J C

机构信息

Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Paris, France.

出版信息

Pharmazie. 1992 Mar;47(3):216-8.

PMID:1615028
Abstract

In this work a study of free cellulose acetate films was carried out in the presence and absence of acacia gum at high concentrations (50 and 75%). The mechanical toughness and the aspect were influenced by operatory conditions and by the relative air humidity. The increase of relative humidity from about 0% to 75% decreased the mechanical toughness and the color film changed from a clear to opaque white. The presence of acacia gum decreased the mechanical toughness and the water vapour transmission rate and increased the film water solubility.

摘要

在这项工作中,对在高浓度(50%和75%)阿拉伯树胶存在和不存在的情况下的游离醋酸纤维素薄膜进行了研究。机械韧性和外观受操作条件和相对空气湿度的影响。相对湿度从约0%增加到75%会降低机械韧性,并且薄膜颜色从透明变为不透明的白色。阿拉伯树胶的存在降低了机械韧性和水蒸气透过率,并增加了薄膜的水溶性。

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