[纵隔生殖细胞肿瘤。治疗策略、预后、生物学特性]
[Germinal tumors of the mediastinum. Therapeutic strategy, prognosis, biology].
作者信息
Droz J P, Ruffié P
机构信息
Département de Médecine, Institut Gustave-Roussy, Villejuif.
出版信息
Rev Mal Respir. 1992;9(3):251-4.
PMID:1615196
Abstract
Mediastinal germ cell tumors have a poor prognosis. Cisplatin containing chemotherapy combined with either primary or post-chemotherapy exeresis of the disease can induce a 50% cure rate. Acute leukemia is often associated with these tumors. In these cases, a clonal evolution from the germ cell tumor has been demonstrated.
摘要
纵隔生殖细胞肿瘤预后较差。含顺铂的化疗联合疾病的初次或化疗后切除可使治愈率达到50%。急性白血病常与这些肿瘤相关。在这些病例中，已证实存在从生殖细胞肿瘤发生的克隆进化。
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