McCabe John E, Jibawi Abdullah, Javle Pradip
Michael Heal Department of Urology, Leighton Hospital, Crewe, UK.
BJU Int. 2005 Oct;96(6):806-10. doi: 10.1111/j.1464-410X.2005.05717.x.
To define 'high-' and 'low-' volume hospitals for radical cystectomy, and the minimum caseload required for a hospital to achieve optimum outcomes, as a relationship between increasing surgical case volume and improved outcomes in radical urological surgery has been suggested in recent North American studies.
All cystectomies for urological cancer in England over 5 years were analysed from Hospital Episode Statistics (HES) data. The data were analysed statistically to describe the relationship between each hospital's annual case volume and two outcome measures: in-hospital mortality rate (MR) and hospital stay.
In all, there were 6317 cystectomies in 210 centres, with an overall MR of 5.6%. There was a significant inverse correlation (-0.733, P < 0.01) between hospital case volume and MR. Applying 95% confidence intervals, the minimum caseload required to achieve optimum outcomes was 11 procedures/year. Increasing the caseload beyond this minimum did not produce a significant reduction in MR.
Analysis of HES data confirms an inverse relationship between hospital caseload and mortality for radical cystectomy. A caseload of 11 operations/year is associated with the lowest MR.
鉴于北美近期研究表明泌尿外科根治性手术的手术例数增加与预后改善之间存在关联,确定根治性膀胱切除术的“高”和“低”手术量医院,以及医院实现最佳预后所需的最低病例数。
从医院事件统计(HES)数据中分析了英格兰5年间所有泌尿外科癌症膀胱切除术的情况。对数据进行统计学分析,以描述每家医院的年病例数与两个预后指标之间的关系:住院死亡率(MR)和住院时间。
210个中心共进行了6317例膀胱切除术,总体死亡率为5.6%。医院病例数与死亡率之间存在显著负相关(-0.733,P<0.01)。应用95%置信区间,实现最佳预后所需的最低病例数为每年11例手术。病例数超过此最低值后,死亡率并未显著降低。
对HES数据的分析证实了医院病例数与根治性膀胱切除术死亡率之间存在负相关。每年11例手术的病例数与最低死亡率相关。