Satti Mohamed B, Batouk Abdelnasir A, Abdelaziz Muntasir M, Ahmad Mohamed F, Abdelaal Mohamed A
Department of Pathology, King Abdul-Aziz Medical City, Jeddah, Jeddah 21423, Kingdom of Saudi Arabia.
Saudi Med J. 2005 Sep;26(9):1459-63.
We report a case of a 30-year-old female who had been treated periodically with steroids for idiopathic thrombocytopenic purpura ITP over the last 10 years. Recently, during the course of investigation, she was found to have incidental asymptomatic multiple pulmonary nodules on chest CT. Following a needle biopsy to exclude malignancy, 2 nodules were excised and were histologically confirmed as pulmonary hyalinizing granuloma PHG. The remaining 2 nodules regressed on increasing her dose of steroids. The case is discussed with emphasis on the histological and radiological differential diagnosis, in addition to including ITP among the spectrum of immunologic conditions associated with PHG.
我们报告一例30岁女性病例，在过去10年中，她因特发性血小板减少性紫癜（ITP）定期接受类固醇治疗。最近，在检查过程中，她的胸部CT发现有偶然的无症状多发肺结节。在进行针吸活检以排除恶性肿瘤后，切除了2个结节，组织学证实为肺透明变性肉芽肿（PHG）。随着类固醇剂量增加，其余2个结节消退。本文讨论了该病例，重点是组织学和放射学鉴别诊断，此外还将ITP纳入与PHG相关的免疫性疾病谱中。
