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[横向电场刺激中周围神经兴奋的实验研究]

[Experimental study of excitation of peripheral nerves in transverse electric field stimulation].

作者信息

Yu Hui, Liu Xueliang, Zheng Chongxun, Wang Yi

机构信息

Institute of Biomedical Engineering, Xi'an Jiaotong University, Xi'an 710049, China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2005 Aug;22(4):654-7.

Abstract

The classical cable function has been used to represent the response of peripheral nerves stimulated by external parallel electric field. Experiments show that peripheral nerves can be activated by perpendicular electric field induced by magnetic pulses, indicating that the activation mechanism needs to be thoroughly investigated. Several excitation properties of peripheral nerves in transverse-field were explored in the present paper. With a human's median nerve in vivo, stimulation threshold, excitation position and the relation between excitation threshold and fiber's radius were studied. The relation between stimulation threshold and stimulation duration was researched with sciatic nerves from toad in vitro. The experimental results verify that the modified cable function is much efficient than the classical cable function. The research will improve the nerve magnetic stimulating technique and be beneficial to further application.

摘要

经典的电缆函数已被用于表示外周神经在外部平行电场刺激下的反应。实验表明,外周神经可被磁脉冲诱导的垂直电场激活,这表明激活机制需要深入研究。本文探讨了外周神经在横向场中的几种激发特性。以人体正中神经为研究对象,在体研究了刺激阈值、激发位置以及激发阈值与纤维半径之间的关系。以蟾蜍离体坐骨神经为研究对象,研究了刺激阈值与刺激持续时间之间的关系。实验结果验证了改进后的电缆函数比经典电缆函数更有效。该研究将改进神经磁刺激技术,有利于进一步应用。

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