早期胎儿超声心动图——一种可靠的产前诊断工具。

Early fetal echocardiography--a reliable prenatal diagnosis tool.

作者信息

McAuliffe Fionnuala M, Trines Jean, Nield Lynne E, Chitayat David, Jaeggi Edgar, Hornberger Lisa K

机构信息

Department of Obstetrics and Gynecology, Mount Sinai Hospital, University of Toronto, Canada.

出版信息

Am J Obstet Gynecol. 2005 Sep;193(3 Pt 2):1253-9. doi: 10.1016/j.ajog.2005.05.086.

DOI:10.1016/j.ajog.2005.05.086

PMID:16157147

Abstract

OBJECTIVE

This study was undertaken to evaluate the feasibility and to report the detection rate of cardiac anomalies with fetal echocardiography before 16 weeks' gestation.

STUDY DESIGN

This is a retrospective and prospective study of 160 early fetal echocardiograms. The mean gestational age was 13.5 weeks' gestation (range 11-15+6). All women had a repeat echocardiogram at 18 weeks' gestation and pregnancy outcome was obtained.

RESULTS

In all cases, a cardiac 4-chamber view was obtained. The atrioventricular valves were accurately seen in 154 (96%) cases; the ascending aorta and main pulmonary artery were visualized in 152 cases (95%). Overall, a satisfactory cardiac examination was feasible in 152 of cases (95%). There were 20 cardiac defects in this cohort (12.5%), 14 showed abnormalities at the time of the early ultrasound, whereas 6 were reported as normal. The sensitivity of early fetal echocardiography in this high-risk population was 70%, specificity 98%, positive predictive value 87.5%, and negative predictive value 96%.

CONCLUSION

The fetal heart can be examined early in pregnancy and a significant proportion of major cardiac defects identified.

摘要

目的

本研究旨在评估妊娠16周前进行胎儿超声心动图检查心脏异常的可行性并报告其检出率。

研究设计

这是一项对160例早期胎儿超声心动图的回顾性和前瞻性研究。平均孕周为13.5周（范围11 - 15⁺⁶周）。所有孕妇在妊娠18周时重复进行超声心动图检查并获得妊娠结局。

结果

所有病例均获得心脏四腔心切面图像。154例（96%）可准确观察到房室瓣；152例（95%）可显示升主动脉和主肺动脉。总体而言，152例（95%）可行满意的心脏检查。该队列中有20例心脏缺陷（12.5%），其中14例在早期超声检查时显示异常，而6例报告为正常。早期胎儿超声心动图在该高危人群中的敏感性为70%，特异性为98%，阳性预测值为87.5%，阴性预测值为96%。