Rupniewska Z M, Wach M, Kowal M, Roliński J, Antosz H
Kliniki Hematologii AM, Lublinie.
Acta Haematol Pol. 1992;23(1):21-7.
This article contains the review and the critical discussion of studies of T and B lymphocytes in chronic B-cell lymphocytic leukaemia. It is not explicitly known now, which stage of differentiation of lympho-haemopoietic cells undergoes malignant transformation in CLL-B. Basing on VDJ recombination activity it is supposed that some cases derive from the stem cell, others--from B lineage cells.
本文包含对慢性B淋巴细胞白血病中T和B淋巴细胞研究的综述及批判性讨论。目前尚不清楚在慢性B淋巴细胞白血病中，淋巴造血细胞的哪个分化阶段发生了恶性转化。基于VDJ重组活性推测，一些病例起源于干细胞，另一些则起源于B系细胞。
