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[应用传染病流行病学/现场流行病学的任务、原则与方法]

[Tasks, principles and methods of applied infectious disease epidemiology/field epidemiology].

作者信息

Hauri A M, Uphoff H

机构信息

Hessisches Landesprüfungs- und Untersuchungsamt im Gesundheitswesen, Dillenburg.

出版信息

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2005 Sep;48(9):1013-9. doi: 10.1007/s00103-005-1119-1.

Abstract

Applied infectious disease epidemiology/field epidemiology involves the application of epidemiologic methods to unexpected health problems when a rapid, on-site investigation is necessary for timely intervention. While field investigations of acute problems share the need of high methodological quality with prospectively planned studies, they may differ in several respects. In particular, because field investigations of ten start without a clear hypothesis, they may require the use of descriptive studies to generate a hypothesis before analytic studies are conducted. There also may be an immediate need to protect the population's health, pressure to intervene may conflict with the need to investigate and publicity may introduce bias. Outbreak investigations are paradigms of the use and methodology of applied infectious disease epidemiology/field epidemiology. The steps of an outbreak investigation include verification, confirming the diagnosis, developing a case definition and case finding, describing the data in terms of time, place and person, risk identification, formulating and testing of a hypothesis, planning for further studies, establishing control measures and communicating the findings.

摘要

应用传染病流行病学/现场流行病学涉及在需要进行快速现场调查以便及时干预时,将流行病学方法应用于突发健康问题。虽然急性问题的现场调查与前瞻性规划研究一样需要高质量的方法,但它们在几个方面可能有所不同。特别是,由于现场调查往往在没有明确假设的情况下开始,因此可能需要在进行分析性研究之前使用描述性研究来生成假设。还可能迫切需要保护人群健康,干预的压力可能与调查的需要相冲突,而且公开信息可能会引入偏差。暴发调查是应用传染病流行病学/现场流行病学的应用和方法的范例。暴发调查的步骤包括核实、确诊、制定病例定义和病例发现、按时间、地点和人物描述数据、识别风险、制定和检验假设、规划进一步研究、建立控制措施以及通报调查结果。

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