4-取代苯甲脒对凝血酶、纤溶酶和胰蛋白酶抑制作用的自由威尔逊分析（作者译）
[Free-Wilson analysis of the inhibitory effect of 4-substituted benzamidines on thrombin, plasmin and trypsin (author's transl)].
作者信息
Labes D, Hagen V
出版信息
Pharmazie. 1979;34(9):554-6.
PMID:161622
Abstract
Using the Fujita-Ban model, the authors studied the quantitative structure-inhibitory activity relationships of a series of 4-amidinophenyl compounds with regard to thrombin, plasmin and trypsin. A satisfactory specification of the inhibitory activities was obtained from activity increments of molecular segments.
摘要
作者使用藤田-班模型研究了一系列4-脒基苯基化合物对凝血酶、纤溶酶和胰蛋白酶的定量构效关系。通过分子片段的活性增量，获得了对抑制活性的满意描述。
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