花菁染料二磺酸-3,3'-二丙基硫代碳菁碘化物（diS-C3-(5)）对艾氏腹水瘤细胞内源性呼吸的抑制机制
The mechanism of inhibition on the endogenous respiration of Ehrlich ascites tumor cells by the cyanine dye diS-C3-(5).
作者信息
Okimasu E, Akiyama J, Shiraishi N, Utsumi K
出版信息
Physiol Chem Phys. 1979;11(5):425-33.
PMID:161623
Abstract
The cyanine dye 3,3'-dipropyl-2,2'-thiadicarbocyanine iodide [diS-C3(5)] was found to be a potent inhibitor of endogenous respiration of Ehrlich ascites tumor cells. This effect is believed to involve both rotenone and uncoupler type actions of the dye on the electron transport system of the mitochondria.
摘要
花青染料3,3'-二丙基-2,2'-硫代二碳菁碘化物[diS-C3(5)]被发现是艾氏腹水瘤细胞内源性呼吸的有效抑制剂。据信，这种作用涉及该染料对线粒体电子传递系统的鱼藤酮和解偶联剂类型的作用。
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