Giuseppetti Gian Marco, Martegani Alberto, Di Cioccio Barbara, Baldassarre Silvia
Istituto di Radiologia, Università Politecnica delle Marche, Azienda Mista Ospedali Riuniti, Facoltà di Medicina, Ancona.
Radiol Med. 2005 Jul-Aug;110(1-2):69-76.
To assess the diagnostic accuracy of elastography in characterising nodular breast lesions.
A total of 82 patients who received mammographic, ultrasonographic and elastographic evaluation in a single session at two Italian centres (Dept of Radiology, Az. Ospedali Riuniti, Ancona, and Ospedale Valduce, Como, Italy) between January and August 2004 according to identical protocols exhibited 91 nodules that were subjected to cytological/histological examination. Lesions were classified and scored and the sensitivity and specificity of elastography calculated.
Overall sensitivity and specificity were 79% and 89%, respectively. However, sensitivity was 86% and 65% and specificity 100% and 62% for lesions < 2 cm and > 2 cm in diameter, respectively. Despite the small sample and the fact that it does not include the full range of cell types, tumour cell composition seemed to affect accuracy.
Elastography is easy and rapid to perform. Larger studies are needed to establish semiological patterns; despite the small patient sample, these data provide an interesting contribution.
评估弹性成像在乳腺结节性病变特征描述中的诊断准确性。
2004年1月至8月期间，在意大利的两个中心（安科纳联合医院放射科以及意大利科莫瓦尔杜切医院），共有82例患者依据相同方案在同一次检查中接受了乳腺X线摄影、超声检查及弹性成像评估，共发现91个结节，并对其进行了细胞学/组织学检查。对病变进行分类和评分，并计算弹性成像的敏感性和特异性。
总体敏感性和特异性分别为79%和89%。然而，直径<2 cm和>2 cm的病变，其敏感性分别为86%和65%，特异性分别为100%和62%。尽管样本量小且未涵盖所有细胞类型，但肿瘤细胞组成似乎会影响准确性。
弹性成像操作简便、快速。需要开展更大规模的研究以建立影像学模式；尽管患者样本量小，但这些数据提供了有价值的参考。
